Prostate cancer affects one in five Australian men, making it the most common cancer in the country. Now, researchers at the Garvan Institute of Medical Research have produced the world's most ...

The rapid development of spatial transcriptomics (ST) technologies has greatly advanced the understanding of gene expression, tissue architecture, cellular composition, and disease mechanisms within ...

Foster City, Calif. | January 27, 2026 — Signios Bio today announced the launch of a new grant program supporting innovative spatial transcriptomics research using the 10x Genomics Xenium 5K Spatial ...

Modern machine learning approaches have shown remarkable success in extracting patterns from high-dimensional biological data. However, when applied to spatial transcriptomics, these methods face ...

Skin cancer is one of the most common malignant tumors worldwide, with its mortality rate showing a significant upward trend, thereby increasing the disease burden on patients and society. With the ...

Vascular smooth muscle cells and pericytes are mural cells that maintain the integrity and support the function of blood vessels. The molecular mechanism underlying the specification of pericytes and ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Unlike animals, plants are sessile organisms that must adapt to localized and fluctuating environmental stimuli, including abiotic and biotic stresses. While animals use mobile immune cells to ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

The tumor microenvironment (TME) of invasive lobular carcinoma (ILC) remains largely unexplored despite its clinical relevance and distinct biology. Using spatial transcriptomics, we reveal insights ...