Morning Overview on MSN
Metabolic enzyme may predict who benefits from cancer immunotherapy
A metabolic enzyme found in the support cells surrounding tumors may hold the key to predicting which cancer patients will ...
The global initiative aims to profile up to 100,000 patient specimens to scale M-Optimus, the world model of biology, representing a ~20x increase in scale over existing data available in the world ...
Hepatocellular carcinoma (HCC) is a highly heterogeneous malignancy characterized by marked cellular and spatial diversity within the tumor microenvironment (TME). The transforming growth factor-β ...
Abstract: Spatial transcriptomics has revolutionized the ability to investigate transcriptional patterns within tissue morphology. However, many ST clustering pipelines operate on a single preselected ...
Foster City, Calif. | January 27, 2026 — Signios Bio today announced the launch of a new grant program supporting innovative spatial transcriptomics research using the 10x Genomics Xenium 5K Spatial ...
Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...
Abstract: Spatial transcriptomics technology enables researchers to acquire both spatial location information and gene expression data within tissues, providing new perspectives for understanding ...
The preprint is available here. DeepSpot2Cell predicts virtual single-cell spatial transcriptomics as follows: (1) During training, the model takes as input (i) the cropped cell tile defined by the ...
(MEMPHIS, Tenn. – December 3, 2025) Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology ...
RNA expression is modulated by tau. We used two mouse models, THY-Tau22 mice, which express pro-aggregation tau, and TauKO mice, which are null for tau, to improve our understanding of tau-altered ...
Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...
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