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To develop a mechanistic physiologically-based model describing CD4 + T-lymphocyte homeostasis across the human lifespan, incorporating maturation, differentiation, migration aspects and the impact of ...

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aKaiser Permanente Southern California Research and Evaluation, 100 S. Los Robles Ave, Pasadena, CA, USA bCentre for Pancreatic Care, Department of Gastroenterology, Los Angeles Medical Centre, ...

A family of delivery approaches where work moves through clearly defined phases in a fixed order, such as requirements, design, development, testing, and release. Each phase must be completed before ...