In conventional pathology and physiology research, two-dimensional (2D) analysis—observing thinly sliced tissue sections—has been mainstream, making it difficult to comprehensively understand the ...

Until now, conventional 3D cell cultures have often been either too rigid or too unstable to realistically reproduce the complex interactions between brain cells. Researchers at Kiel University (CAU) ...

The origin of many diseases begins at the cellular level and involves multiple molecular interactions. However, previous methods have struggled to accurately observe changes in individual cells.

Most cells in the human body exist in complex three-dimensional environments, yet they are still commonly studied on flat plastic dishes. These two-dimensional cultures distort cell behavior, limiting ...

Growing cells in three dimensions is critical for studying how tissues behave in the body, yet most laboratory platforms remain either too simple or too complex to use widely. Researchers now present ...

Researchers developed a microfluidic chip with 3D-printed microstructures that moves droplets precisely, captures cells efficiently, and quickly forms cell spheroids for improved lab-grown tissue ...

Human cells are extremely small and tightly packed – at about 20 micrometers across, roughly one-fifth the width of a human hair, each cell contains a dense mix of proteins, organelles, and molecular ...

A novel method has enabled scientists to 3D-print structures into live cells, paving the way for a new class of intracellular bioengineering tools and applications. In a first, scientists from the ...

MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, tiny loops called microcompartments remain (and even strengthen) while ...

Researchers are increasingly shifting from simple to complex models to better recapitulate diseases. As they move from immortalized cell lines to more physiologically relevant systems such as ...

3D cell cultures are no longer a futuristic idea. They’re already reshaping how we study diseases like cancer, offering more realistic models of how cells behave in the body. But despite their ...