Denali Therapeutics’ tividenofusp alfa (Avlayah) has secured accelerated approval for Hunter syndrome, a rare metabolic disease. The first-in-modality biologic — an enzyme fused to a blood–brain ...

Hunter syndrome patients can manage the disorder with a drug that addresses disease symptoms throughout the body except the brain — a key limitation for treating this rare neurological disorder. The ...

Katie has a PhD in maths, specializing in the intersection of dynamical systems and number theory. She reports on topics from maths and history to society and animals. Katie has a PhD in maths, ...

Please provide your email address to receive an email when new articles are posted on . Hand-foot syndrome is a painful adverse event from chemotherapy, particularly capecitabine. Data show an ...

AHS is often caused by brain injury or neurodegenerative illnesses, but there is not enough research to determine any consistent cause or why it occurs. “Alien hand is little investigated because it ...

Scientists have discovered three genes to be master regulators that reshape gene activity across the developing Down syndrome brain. By tracing how these regulators disrupt networks tied to learning ...

Scientists from Duke-NUS Medical School, working with collaborators at Imperial College London and partners in Europe and the United States, have uncovered new insights into how an additional copy of ...

Summary: Rett syndrome is primarily understood as a neuronal disorder, but new evidence suggests that the “plumbing” of the brain may be just as important as its wiring. A landmark study reveals that ...

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Scientific literature is, to say the least, pretty dull. It's rife with redundant phrases, confusing methodologies, and tiny graphs. Reading page after page of long words in small font is better than ...