In the spring of 1966, Stewart Brand did 100 micrograms of LSD and sat on top of a roof in San Francisco. Perched there, he looked toward a curved horizon and imagined the spherical Earth and just how ...

A person with naturally occurring synesthesia experiences the sensory world in overlapping layers. Sounds are seen as colors and tastes are processed as sounds. Overall, there are 60 documented forms ...

Before Timothy Leary came along, psychedelic drugs were respectable. The American public’s introduction to these substances was gradual, considered, and enthusiastic. Psilocybin appeared in an article ...

Scientists have designed compounds that hit the same key receptor that LSD activates without causing hallucinations. A single dose produced powerful antidepressant and antianxiety effects in mice that ...