Genetic circuit engineering is the synthesis of unnatural DNA segments encoding protein or RNA molecules that control each other’s levels. Genetic circuit engineering is the bottom-up, local approach ...

This study demonstrates that 16p11.2 hemideletion, a genetic deletion linked to neurodevelopmental disorders, affects male and female mice differently, altering specific striatal neuronal circuits and ...

This important study combines optogenetic manipulations and wide-field imaging to show that the retrosplenial cortex controls behavioral responses to whisker deflection in a context-dependent manner.