Mast cells are the progeny of hematopoietic stem cells, and murine mast cells are usually divided into two distinct populations, mucosal mast cells (MMCs) and connective tissue-type mast cells (CTMCs) ...

Classical Ehlers-Danlos syndrome (previously known as EDS type I/II) is an inheritable connective tissue disorder that involves skin, tendons, ligaments, and, in some cases, also blood vessels. Most ...

Genetic studies have revealed many genes linked to both common and rare disease, but to understand how those genes bring about disease and use those insights to help develop therapies, scientists need ...

Suggested Citation: "1 Introduction." National Academies of Sciences, Engineering, and Medicine. 2022. Selected Heritable Disorders of Connective Tissue and Disability. Washington, DC: The National ...

Undifferentiated connective tissue disease (UCTD) is a type of autoimmune disease. It can cause symptoms like joint pain and swelling, skin symptoms, and more. The exact prevalence of UCTD is unknown, ...

The international standard for the classification and nomenclature of histologies is the International Classification of Diseases for Oncology, Third Edition (ICD-O-3). This classification is based on ...