引言当我们能够以极快的速度测序出一个又一个物种的基因组时，生命科学领域正面临着一个日益严峻的尴尬局面：我们掌握了海量的由A、T、C、G组成的生命“字母表”，却越来越难以准确读懂这些字母所拼凑出的“词汇”和“句子”。为了打破这一将基因组序列映射到生物学功能的瓶颈，3月12日《Nature ...

The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...

RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...

High background noise in RNA samples can impact read accuracy and increase sequencing costs. Optimizing sample quality enables better microRNA mapping and more reliable insights in transcriptomics and ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

A new sequencing-based method uses molecular barcodes to trace synaptic connections among neurons. The approach enables large ...

In this Teach Me in 10 episode, Dr. Shaveta Goyal, Group Leader of NGS at Takara Bio USA, outlines the practical considerations that matter most when selecting an RNA-seq workflow.<br /><br /> ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

Researchers at Karolinska Institutet have developed a rapid and cost-efficient sequencing method that can identify antibiotic ...

Microscopic images of human tissue are a cornerstone of biomedical research and clinical diagnostics. Yet despite their importance, these images often remain difficult to analyze systematically and to ...