While fuorescence has become the dominant mode in biological microscopy nowadays for its high molecular contrast, the capability of other modes based on scattering, polarization, and interference, and ...

The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...

Fluorescence microscopy techniques are powerful tools for probing very small signals and revealing three-dimensional (3D) structural and functional properties of biological samples with high ...

This article describes a six-inch wafer inspection microscope that provides automated, reproducible differential interference contrast (DIC) imaging, regardless of the user’s skill level. Wafer ...

The use of high-resolution bright-field microscopy is essential for cellular-scale biological research, but this technique has limitations due to low image contrast. Using dyes on the sample can ...