Replication fork reversal is a complex transaction that requires the coordinated unwinding and annealing of parental and newly synthesized strands at the replication fork. Replication fork reversal is ...

Our lab studies the mechanism of eukaryotic chromosome replication. Chromosomes are the carriers of the genetic and epigenetic information and faithful chromosome replication is of fundamental ...

The replication of DNA is initiated at particular sites on the genome called replication origins (ROs). Understanding the constraints that regulate the distribution of ROs across different organisms ...

The capabilities of organisms to contend with environmental changes depend on their genes and their ability to regulate their expression. DNA-binding transcription factors (TFs) play a central role in ...

Could yeast and humans be any more different? Going by looks alone, probably not. But peering into our genomes reveals ...