DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

After decades of mystery, scientists have finally figured out the structure of a key herpes virus protein that is vital for ...

Breakthrough cryo-EM structures expose multiple drug targets in an essential HSV-1 replication protein.An international research team has determined ...

An international research team has determined the first high-resolution structures of the herpes simplex virus origin-binding protein (OBP), a critical component of viral DNA replication that has ...